Endothelial senescence mediates hypoxia-induced vascular remodeling by modulating PDGFB expression

Uncontrolled accumulation of pulmonary artery smooth muscle cells (PASMCs) to the distal pulmonary arterioles (PAs) is one of the major characteristics of pulmonary hypertension (PH). Cellular senescence contributes to aging and lung diseases associated with PH and links to PH progression. However,...

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Detalles Bibliográficos
Autores principales: Kyi, Priscilla, Hendee, Kathryn, Hunyenyiwa, Tendai, Matus, Kienna, Mammoto, Tadanori, Mammoto, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530050/
https://www.ncbi.nlm.nih.gov/pubmed/36203755
http://dx.doi.org/10.3389/fmed.2022.908639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530050/
https://www.ncbi.nlm.nih.gov/pubmed/36203755
http://dx.doi.org/10.3389/fmed.2022.908639

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