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HOXA9 has the hallmarks of a biological switch with implications in blood cancers

Blood malignancies arise from the dysregulation of haematopoiesis. The type of blood cell and the specific order of oncogenic events initiating abnormal growth ultimately determine the cancer subtype and subsequent clinical outcome. HOXA9 plays an important role in acute myeloid leukaemia (AML) prog...

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Detalles Bibliográficos
Autores principales: Talarmain, Laure, Clarke, Matthew A., Shorthouse, David, Cabrera-Cosme, Lilia, Kent, David G., Fisher, Jasmin, Hall, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530117/
https://www.ncbi.nlm.nih.gov/pubmed/36192425
http://dx.doi.org/10.1038/s41467-022-33189-w