Regulation of KDM5C stability and enhancer reprogramming in breast cancer

Abnormality of enhancer regulation has emerged as one of the critical features for cancer cells. KDM5C is a histone H3K4 demethylase and frequently mutated in several types of cancer. It is critical for H3K4me3 and activity of enhancers, but its regulatory mechanisms remain elusive. Here, we identif...

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Detalles Bibliográficos
Autores principales: Xiao, Qiong, Wang, Chen-Yu, Gao, Chuan, Chen, Ji-Dong, Chen, Jing-Jing, Wang, Zhen, Ju, Lin-Gao, Tang, Shan-Bo, Yao, Jie, Li, Feng, Li, Lian-Yun, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530161/
https://www.ncbi.nlm.nih.gov/pubmed/36192394
http://dx.doi.org/10.1038/s41419-022-05296-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530161/
https://www.ncbi.nlm.nih.gov/pubmed/36192394
http://dx.doi.org/10.1038/s41419-022-05296-5

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