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Regulation of KDM5C stability and enhancer reprogramming in breast cancer
Abnormality of enhancer regulation has emerged as one of the critical features for cancer cells. KDM5C is a histone H3K4 demethylase and frequently mutated in several types of cancer. It is critical for H3K4me3 and activity of enhancers, but its regulatory mechanisms remain elusive. Here, we identif...
Autores principales: | Xiao, Qiong, Wang, Chen-Yu, Gao, Chuan, Chen, Ji-Dong, Chen, Jing-Jing, Wang, Zhen, Ju, Lin-Gao, Tang, Shan-Bo, Yao, Jie, Li, Feng, Li, Lian-Yun, Wu, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530161/ https://www.ncbi.nlm.nih.gov/pubmed/36192394 http://dx.doi.org/10.1038/s41419-022-05296-5 |
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