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Timing of vagus nerve stimulation during fear extinction determines efficacy in a rat model of PTSD

Studies have indicated that vagus nerve stimulation (VNS) enhances extinction learning in rodent models. Here, we investigated if pairing VNS with the conditioned stimulus is required for the enhancing effects of VNS. Adult Sprague–Dawley rats were exposed to intense stress followed by fear conditio...

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Detalles Bibliográficos
Autores principales: Souza, Rimenez R., Powers, Mark B., Rennaker, Robert L., McIntyre, Christa K., Hays, Seth A., Kilgard, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530175/
https://www.ncbi.nlm.nih.gov/pubmed/36192564
http://dx.doi.org/10.1038/s41598-022-20301-9