Circulating CD81-expressing extracellular vesicles as biomarkers of response for immune-checkpoint inhibitors in advanced NSCLC

PD-L1 in tumor cells is the only used biomarker for anti PD1/PD-L1 immune-checkpoints inhibitors (ICI) in Non Small Cell Lung Cancer (NSCLC) patients. However, this parameter is inaccurate to predict response, especially in patients with low tumor PD-L1. Here, we evaluated circulating EVs as possibl...

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Detalles Bibliográficos
Autores principales: Signorelli, Diego, Ghidotti, Patrizia, Proto, Claudia, Brambilla, Marta, De Toma, Alessandro, Ferrara, Roberto, Galli, Giulia, Ganzinelli, Monica, Lo Russo, Giuseppe, Prelaj, Arsela, Occhipinti, Mario, Viscardi, Giuseppe, Capizzuto, Valentina, Pontis, Francesca, Petraroia, Ilaria, Ferretti, Anna Maria, Colombo, Mario Paolo, Torri, Valter, Sozzi, Gabriella, Garassino, Marina Chiara, Jachetti, Elena, Fortunato, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530186/
https://www.ncbi.nlm.nih.gov/pubmed/36203609
http://dx.doi.org/10.3389/fimmu.2022.987639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530186/
https://www.ncbi.nlm.nih.gov/pubmed/36203609
http://dx.doi.org/10.3389/fimmu.2022.987639

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