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IL12 immune therapy clinical trial review: Novel strategies for avoiding CRS-associated cytokines

Interleukin 12 (IL-12) is a naturally occurring cytokine that plays a key role in inducing antitumor immune responses, including induction of antitumor immune memory. Currently, no IL-12-based therapeutic products have been approved for clinical application because of its toxicities. On the basis of...

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Detalles Bibliográficos
Autores principales: Jia, Zhiliang, Ragoonanan, Dristhi, Mahadeo, Kris Michael, Gill, Jonathan, Gorlick, Richard, Shpal, Elizabeth, Li, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530253/
https://www.ncbi.nlm.nih.gov/pubmed/36203573
http://dx.doi.org/10.3389/fimmu.2022.952231