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IL12 immune therapy clinical trial review: Novel strategies for avoiding CRS-associated cytokines
Interleukin 12 (IL-12) is a naturally occurring cytokine that plays a key role in inducing antitumor immune responses, including induction of antitumor immune memory. Currently, no IL-12-based therapeutic products have been approved for clinical application because of its toxicities. On the basis of...
Autores principales: | Jia, Zhiliang, Ragoonanan, Dristhi, Mahadeo, Kris Michael, Gill, Jonathan, Gorlick, Richard, Shpal, Elizabeth, Li, Shulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530253/ https://www.ncbi.nlm.nih.gov/pubmed/36203573 http://dx.doi.org/10.3389/fimmu.2022.952231 |
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