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GLUD1 suppresses renal tumorigenesis and development via inhibiting PI3K/Akt/mTOR pathway
Growing cancer cells are addicted to glutamine. Glutamate dehydrogenase 1 (GLUD1) is one of key enzymes in glutamine metabolism and plays a critical role in the malignancy of diverse tumors. However, its role and molecular mechanism in clear cell renal cell carcinoma (ccRCC) development and progress...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530280/ https://www.ncbi.nlm.nih.gov/pubmed/36203437 http://dx.doi.org/10.3389/fonc.2022.975517 |