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GLUD1 suppresses renal tumorigenesis and development via inhibiting PI3K/Akt/mTOR pathway

Growing cancer cells are addicted to glutamine. Glutamate dehydrogenase 1 (GLUD1) is one of key enzymes in glutamine metabolism and plays a critical role in the malignancy of diverse tumors. However, its role and molecular mechanism in clear cell renal cell carcinoma (ccRCC) development and progress...

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Detalles Bibliográficos
Autores principales:	Wang, Lei, Fang, Zhiyu, Gao, Peixiang, Zheng, Junfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530280/ https://www.ncbi.nlm.nih.gov/pubmed/36203437 http://dx.doi.org/10.3389/fonc.2022.975517

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