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IFN-γ transforms the transcriptomic landscape and triggers myeloid cell hyperresponsiveness to cause lethal lung injury

Acute Respiratory Distress Syndrome (ARDS) is an inflammatory disease that is associated with high mortality but no specific treatment. Our understanding of initial events that trigger ARDS pathogenesis is limited. We have developed a mouse model of inflammatory lung injury by influenza and methicil...

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Detalles Bibliográficos
Autores principales: Verma, Atul K., McKelvey, Michael, Uddin, Md Bashir, Palani, Sunil, Niu, Meng, Bauer, Christopher, Shao, Shengjun, Sun, Keer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530332/
https://www.ncbi.nlm.nih.gov/pubmed/36203588
http://dx.doi.org/10.3389/fimmu.2022.1011132