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IFN-γ transforms the transcriptomic landscape and triggers myeloid cell hyperresponsiveness to cause lethal lung injury
Acute Respiratory Distress Syndrome (ARDS) is an inflammatory disease that is associated with high mortality but no specific treatment. Our understanding of initial events that trigger ARDS pathogenesis is limited. We have developed a mouse model of inflammatory lung injury by influenza and methicil...
Autores principales: | Verma, Atul K., McKelvey, Michael, Uddin, Md Bashir, Palani, Sunil, Niu, Meng, Bauer, Christopher, Shao, Shengjun, Sun, Keer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530332/ https://www.ncbi.nlm.nih.gov/pubmed/36203588 http://dx.doi.org/10.3389/fimmu.2022.1011132 |
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