AZD6738 Inhibits fibrotic response of conjunctival fibroblasts by regulating checkpoint kinase 1/P53 and PI3K/AKT pathways

Trabeculectomy can effectively reduce intraocular pressure (IOP) in glaucoma patients, the long-term surgical failure is due to the excessive proliferation and fibrotic response of conjunctival fibroblasts which causes the subconjunctival scar and non-functional filtering bleb. In this study, we dem...

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Detalles Bibliográficos
Autores principales: Huang, Longxiang, Ye, Qin, Lan, Chunlin, Wang, Xiaohui, Zhu, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530343/
https://www.ncbi.nlm.nih.gov/pubmed/36204234
http://dx.doi.org/10.3389/fphar.2022.990401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530343/
https://www.ncbi.nlm.nih.gov/pubmed/36204234
http://dx.doi.org/10.3389/fphar.2022.990401

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