Protease-activated receptor 2 promotes clearance of Pseudomonas aeruginosa infection by inducing cAMP-Rac1 signaling in alveolar macrophages

Efficient phagocytosis of pathogens by the innate immune system during infectious injury is vital for restoring tissue integrity. Impaired phagocytosis, such as in the case of infection with Pseudomonas aeruginosa, a broad-spectrum antibiotic-resistant Gram-negative bacterium, can lead to a life thr...

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Detalles Bibliográficos
Autores principales: Rayees, Sheikh, Joshi, Jagdish Chandra, Joshi, Bhagwati, Vellingiri, Vigneshwaran, Banerjee, Somenath, Mehta, Dolly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530345/
https://www.ncbi.nlm.nih.gov/pubmed/36204227
http://dx.doi.org/10.3389/fphar.2022.874197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530345/
https://www.ncbi.nlm.nih.gov/pubmed/36204227
http://dx.doi.org/10.3389/fphar.2022.874197

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