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Transcriptional programming of immunoregulatory responses in human Langerhans cells

Human epidermal Langerhans cells (LCs) maintain immune homeostasis in the skin. To examine transcriptional programming of human primary LCs during homeostasis, we performed scRNA-seq analysis of LCs before and after migration from the epidermis, coupled with functional assessment of their regulatory...

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Detalles Bibliográficos
Autores principales: Davies, James, Sirvent, Sofia, Vallejo, Andres F., Clayton, Kalum, Douilhet, Gemma, Keeler, Patrick S., West, Jonathan, Ardern-Jones, Michael, MacArthur, Ben D., Singh, Harinder, Polak, Marta E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530347/
https://www.ncbi.nlm.nih.gov/pubmed/36203560
http://dx.doi.org/10.3389/fimmu.2022.892254