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mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma

BACKGROUND: Thyroid hormones (THs) inhibit hepatocellular carcinoma (HCC) through different mechanisms. However, whether microRNAs play a role in the antitumorigenic effect of THs remains unknown. METHODS: By next generation sequencing (NGS) we performed a comprehensive comparative miRNomic and tran...

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Detalles Bibliográficos
Autores principales: Serra, Marina, Pal, Rajesh, Puliga, Elisabetta, Sulas, Pia, Cabras, Lavinia, Cusano, Roberto, Giordano, Silvia, Perra, Andrea, Columbano, Amedeo, Kowalik, Marta Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530455/
https://www.ncbi.nlm.nih.gov/pubmed/36203462
http://dx.doi.org/10.3389/fonc.2022.941552