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Aptamer-conjugated graphene oxide-based surface assisted laser desorption ionization mass spectrometry for selective extraction and detection of Aβ(1–42) in an Alzheimer’s disease SH-SY5 cell model
The generation and accumulation of amyloid-beta peptide (Aβ(1–42)) in amyloid plaques are key characteristics of Alzheimer’s disease (AD); thus, specific detection of Aβ(1–42) is essential for the diagnosis and treatment of AD. Herein, an aptamer-conjugated graphene oxide (Apt-GO) sensor was synthes...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530460/ https://www.ncbi.nlm.nih.gov/pubmed/36204557 http://dx.doi.org/10.3389/fnagi.2022.993281 |