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Aptamer-conjugated graphene oxide-based surface assisted laser desorption ionization mass spectrometry for selective extraction and detection of Aβ(1–42) in an Alzheimer’s disease SH-SY5 cell model

The generation and accumulation of amyloid-beta peptide (Aβ(1–42)) in amyloid plaques are key characteristics of Alzheimer’s disease (AD); thus, specific detection of Aβ(1–42) is essential for the diagnosis and treatment of AD. Herein, an aptamer-conjugated graphene oxide (Apt-GO) sensor was synthes...

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Detalles Bibliográficos
Autores principales:	Song, Gongshuai, Shui, Ruofan, Wang, Danli, Fang, Ruosi, Yuan, Tinglan, Li, Ling, Feng, Junli, Gao, Feng, Shen, Qing, Gong, Jinyan, Zheng, Fuping, Zhang, Manman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530460/ https://www.ncbi.nlm.nih.gov/pubmed/36204557 http://dx.doi.org/10.3389/fnagi.2022.993281

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