Lipid droplet accumulation in β cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and β cell dysfunction involving decreased insulin granules

BACKGROUND AND OBJECTIVE: Pancreatic fat is a form of ectopic fat. Lipid droplets (LDs) are also observed in β cells; however, the pathophysiological significance, especially for β cell function, has not been elucidated. Our aim was to assess LD accumulation in β cells in various stages of glucose i...

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Detalles Bibliográficos
Autores principales: Horii, Tomomi, Kozawa, Junji, Fujita, Yukari, Kawata, Satoshi, Ozawa, Harutoshi, Ishibashi, Chisaki, Yoneda, Sho, Nammo, Takao, Miyagawa, Jun-ichiro, Eguchi, Hidetoshi, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530467/
https://www.ncbi.nlm.nih.gov/pubmed/36204103
http://dx.doi.org/10.3389/fendo.2022.996716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530467/
https://www.ncbi.nlm.nih.gov/pubmed/36204103
http://dx.doi.org/10.3389/fendo.2022.996716

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