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Oxidized low-density lipoprotein causes ribosome reduction and inhibition of protein synthesis in retinal pigment epithelial cells

Retinal pigment epithelium (RPE) are specialized multifunctional cells indispensable for maintenance of vision. Dysfunction and death of the RPE cells is implicated in the genesis and progression of age-related macular degeneration (AMD). Oxidative stress and resulting cellular damage plays a critic...

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Detalles Bibliográficos
Autores principales: Giorgianni, Francesco, Beranova-Giorgianni, Sarka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530482/
https://www.ncbi.nlm.nih.gov/pubmed/36204727
http://dx.doi.org/10.1016/j.bbrep.2022.101345