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Altered muscle oxidative phenotype impairs exercise tolerance but does not improve after exercise training in multiple sclerosis

BACKGROUND: Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This study aimed to determine the contributions of the cardiopulmonary system and peripheral...

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Detalles Bibliográficos
Autores principales: Spaas, Jan, Goulding, Richie P., Keytsman, Charly, Fonteyn, Lena, van Horssen, Jack, Jaspers, Richard T., Eijnde, Bert O., Wüst, Rob C.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530506/
https://www.ncbi.nlm.nih.gov/pubmed/35929063
http://dx.doi.org/10.1002/jcsm.13050