Sphingomyelinase activity promotes atrophy and attenuates force in human muscle fibres and is elevated in heart failure patients

BACKGROUND: Activation of sphingomyelinase (SMase) as a result of a general inflammatory response has been implicated as a mechanism underlying disease‐related loss of skeletal muscle mass and function in several clinical conditions including heart failure. Here, for the first time, we characterize...

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Detalles Bibliográficos
Autores principales: Olsson, Karl, Cheng, Arthur J., Al‐Ameri, Mamdoh, Tardif, Nicolas, Melin, Michael, Rooyackers, Olav, Lanner, Johanna T., Westerblad, Håkan, Gustafsson, Thomas, Bruton, Joseph D., Rullman, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530516/
https://www.ncbi.nlm.nih.gov/pubmed/35852046
http://dx.doi.org/10.1002/jcsm.13029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530516/
https://www.ncbi.nlm.nih.gov/pubmed/35852046
http://dx.doi.org/10.1002/jcsm.13029

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