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The impaired distribution of adenosine deaminase isoenzymes in multiple sclerosis plasma and cerebrospinal fluid

BACKGROUND: Adenosine deaminase (ADA) via two isoenzymes, ADA1 and ADA2, regulates intra- and extracellular adenosine concentrations by converting it to inosine. In the central nervous system (CNS), adenosine modulates the processes of neuroinflammation and demyelination that together play a critica...

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Detalles Bibliográficos
Autores principales: Kutryb-Zajac, Barbara, Kawecka, Ada, Caratis, Fionä, Urbanowicz, Krzysztof, Braczko, Alicja, Furihata, Tomomi, Karaszewski, Bartosz, Smolenski, Ryszard T., Rutkowska, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530629/
https://www.ncbi.nlm.nih.gov/pubmed/36204140
http://dx.doi.org/10.3389/fnmol.2022.998023