Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines

Immune checkpoint blockade is therapeutically successful for many patients across multiple cancer types. However, immune-related adverse events (irAE) frequently occur and can sometimes be life threatening. It is critical to understand the immunologic mechanisms of irAEs with the goal of finding nov...

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Detalles Bibliográficos
Autores principales: Reschke, Robin, Shapiro, Jason W., Yu, Jovian, Rouhani, Sherin J., Olson, Daniel J., Zha, Yuanyuan, Gajewski, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Priority Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530647/
https://www.ncbi.nlm.nih.gov/pubmed/35977003
http://dx.doi.org/10.1158/2326-6066.CIR-22-0362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530647/
https://www.ncbi.nlm.nih.gov/pubmed/35977003
http://dx.doi.org/10.1158/2326-6066.CIR-22-0362

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