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Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines
Immune checkpoint blockade is therapeutically successful for many patients across multiple cancer types. However, immune-related adverse events (irAE) frequently occur and can sometimes be life threatening. It is critical to understand the immunologic mechanisms of irAEs with the goal of finding nov...
Autores principales: | Reschke, Robin, Shapiro, Jason W., Yu, Jovian, Rouhani, Sherin J., Olson, Daniel J., Zha, Yuanyuan, Gajewski, Thomas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530647/ https://www.ncbi.nlm.nih.gov/pubmed/35977003 http://dx.doi.org/10.1158/2326-6066.CIR-22-0362 |
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