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Imaging Glioblastoma Response to Radiotherapy Using (2)H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism

Early detection of tumor cell death in glioblastoma following treatment with chemoradiation has the potential to distinguish between true disease progression and pseudoprogression. Tumor cell death can be detected noninvasively in vivo by imaging the production of [2,3-(2)H(2)]malate from [2,3-(2)H(...

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Detalles Bibliográficos
Autores principales: Hesse, Friederike, Wright, Alan J., Somai, Vencel, Bulat, Flaviu, Kreis, Felix, Brindle, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530651/
https://www.ncbi.nlm.nih.gov/pubmed/35972377
http://dx.doi.org/10.1158/0008-5472.CAN-22-0101