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Unbiased screen for pathogens in human paraffin-embedded tissue samples by whole genome sequencing and metagenomics

Identification of bacterial pathogens in formalin fixed, paraffin embedded (FFPE) tissue samples is limited to targeted and resource-intensive methods such as sequential PCR analyses. To enable unbiased screening for pathogens in FFPE tissue samples, we established a whole genome sequencing (WGS) me...

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Detalles Bibliográficos
Autores principales: Nienhold, Ronny, Mensah, Nadine, Frank, Angela, Graber, Anne, Koike, Jacqueline, Schwab, Nathalie, Hernach, Claudia, Zsikla, Veronika, Willi, Niels, Cathomas, Gieri, Hamelin, Baptiste, Graf, Susanne, Junt, Tobias, Mertz, Kirsten D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530700/
https://www.ncbi.nlm.nih.gov/pubmed/36204644
http://dx.doi.org/10.3389/fcimb.2022.968135