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A Ferrier glycosylation/cis-dihydroxylation strategy to synthesize Leishmania spp. lipophosphoglycan-associated βGal(1,4)Man disaccharide

The Galβ(1→4)Man disaccharide, found in the cell surface lipophosphoglycan (LPG) of Leishmania species, has been synthesized by a Ferrier glycosylation/cis-dihydroxylation strategy. This stereoselective method proved efficient for synthesizing the target saccharide in good yield. In addition, we pre...

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Detalles Bibliográficos
Autores principales: Budhathoki, Dipesh, Deore, Bhavesh, Finn, M. G., Sanhueza, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530798/
https://www.ncbi.nlm.nih.gov/pubmed/36320230
http://dx.doi.org/10.1039/d2ra05158c