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Unleashing high content screening in hit detection – Benchmarking AI workflows including novelty detection

Complex mixtures containing natural products are still an interesting source of novel drug candidates. High content screening (HCS) is a popular tool to screen for such. In particular, multiplexed HCS assays promise comprehensive bioactivity profiles, but generate also high amounts of data. Yet, onl...

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Detalles Bibliográficos
Autores principales: Kupczyk, Erwin, Schorpp, Kenji, Hadian, Kamyar, Lin, Sean, Tziotis, Dimitrios, Schmitt-Kopplin, Philippe, Mueller, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530837/
https://www.ncbi.nlm.nih.gov/pubmed/36212538
http://dx.doi.org/10.1016/j.csbj.2022.09.023