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Ubiquitin‐specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma

Overexpression of ubiquitin‐specific protease 28 (USP28) is found in hepatic carcinoma. It is unclear whether the deubiquitinase plays a role in hepatocarcinogenesis. Deregulation of the Wnt signaling pathway is frequently associated with liver cancer. Transcription factor 7‐like 2 (TCF7L2) is an im...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Cai, Mengjiao, Wu, Lingzhi, Zhen, Xinghua, Chen, Yuetong, Peng, Jin, Han, Suxia, Zhang, Pumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530868/
https://www.ncbi.nlm.nih.gov/pubmed/35880246
http://dx.doi.org/10.1111/cas.15509