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HBV immune tolerance of HBs-transgenic mice observed through parabiosis with WT mice

It was extensively recognized that central tolerance to HBV exists in HBs-transgenic (Tg) mice, however, the immune response to HBV vaccine may be inspired in adult HBs-Tg mice after boosting with potent adjuvants, leaving a mystery to explore its immune tolerance. Here, WT-HBs-Tg parabiotic mice mo...

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Detalles Bibliográficos
Autores principales: Zhang, Wendi, Sun, Haoyu, Sun, Rui, Lian, Zhexiong, Wei, Haiming, Tian, Zhigang, Chen, Yongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530942/
https://www.ncbi.nlm.nih.gov/pubmed/36203595
http://dx.doi.org/10.3389/fimmu.2022.993246