Lysosomal acid lipase deficiency: A rare inherited dyslipidemia but potential ubiquitous factor in the development of atherosclerosis and fatty liver disease

Lysosomal acid lipase (LAL), encoded by the gene LIPA, is the sole neutral lipid hydrolase in lysosomes, responsible for cleavage of cholesteryl esters and triglycerides into their component parts. Inherited forms of complete (Wolman Disease, WD) or partial LAL deficiency (cholesteryl ester storage...

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Detalles Bibliográficos
Autores principales: Besler, Katrina J., Blanchard, Valentin, Francis, Gordon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530988/
https://www.ncbi.nlm.nih.gov/pubmed/36204319
http://dx.doi.org/10.3389/fgene.2022.1013266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530988/
https://www.ncbi.nlm.nih.gov/pubmed/36204319
http://dx.doi.org/10.3389/fgene.2022.1013266

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