Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata

Alopecia areata (AA) is an autoimmune disease caused by T cell-mediated destruction of the hair follicle (HF). Therefore, approaches that effectively disrupt pathogenic T cell responses are predicted to have therapeutic benefit for AA treatment. T cells rely on the duality of T cell receptor (TCR) a...

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Detalles Bibliográficos
Autores principales: Dai, Zhenpeng, Sezin, Tanya, Chang, Yuqian, Lee, Eunice Y., Wang, Eddy Hsi Chun, Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531018/
https://www.ncbi.nlm.nih.gov/pubmed/36203601
http://dx.doi.org/10.3389/fimmu.2022.955038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531018/
https://www.ncbi.nlm.nih.gov/pubmed/36203601
http://dx.doi.org/10.3389/fimmu.2022.955038

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