Effect of an autism-associated KCNMB2 variant, G124R, on BK channel properties

BK K(+) channels are critical regulators of neuron and muscle excitability, comprised of a tetramer of pore-forming αsubunits from the KCNMA1 gene and cell- and tissue-selective β subunits (KCNMB1-4). Mutations in KCNMA1 are associated with neurological disorders, including autism. However, little i...

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Detalles Bibliográficos
Autores principales: Moldenhauer, Hans J., Dinsdale, Ria L., Alvarez, Sara, Fernández-Jaén, Alberto, Meredith, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531041/
https://www.ncbi.nlm.nih.gov/pubmed/36203817
http://dx.doi.org/10.1016/j.crphys.2022.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531041/
https://www.ncbi.nlm.nih.gov/pubmed/36203817
http://dx.doi.org/10.1016/j.crphys.2022.09.001

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