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Effect of an autism-associated KCNMB2 variant, G124R, on BK channel properties
BK K(+) channels are critical regulators of neuron and muscle excitability, comprised of a tetramer of pore-forming αsubunits from the KCNMA1 gene and cell- and tissue-selective β subunits (KCNMB1-4). Mutations in KCNMA1 are associated with neurological disorders, including autism. However, little i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531041/ https://www.ncbi.nlm.nih.gov/pubmed/36203817 http://dx.doi.org/10.1016/j.crphys.2022.09.001 |