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The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation

The Endoplasmic Reticulum Aminopeptidase 1 and 2 (ERAP1 and ERAP2) and Insulin Regulated Aminopeptidase (IRAP) are three M1 zinc metalloproteases whose role in antigen processing is the refining of peptidome either in the Endoplasmic reticulum (ERAP1 and ERAP2), or in the endosomes (IRAP). However,...

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Detalles Bibliográficos
Autores principales: Mattorre, Benedetta, Tedeschi, Valentina, Paldino, Giorgia, Fiorillo, Maria Teresa, Paladini, Fabiana, Sorrentino, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531115/
https://www.ncbi.nlm.nih.gov/pubmed/36203608
http://dx.doi.org/10.3389/fimmu.2022.1002375