Distinct mechanism of cervical cancer cell death caused by the investigational new drug SHetA2

Drug-targetable vulnerabilities of cancer cells include their dependence on heat shock proteins (HSPs) to support elevated mitochondrial metabolism and counteract cell death factors. The investigational new drug SHetA2 targets these vulnerabilities in ovarian and endometrial cancer cells by disrupti...

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Detalles Bibliográficos
Autores principales: Rai, Rajani, Chandra, Vishal, Kennedy, Amy L., Zuna, Rosemary E., Benbrook, Doris Mangiaracina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531157/
https://www.ncbi.nlm.nih.gov/pubmed/36203464
http://dx.doi.org/10.3389/fonc.2022.958536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531157/
https://www.ncbi.nlm.nih.gov/pubmed/36203464
http://dx.doi.org/10.3389/fonc.2022.958536

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