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Distinct mechanism of cervical cancer cell death caused by the investigational new drug SHetA2
Drug-targetable vulnerabilities of cancer cells include their dependence on heat shock proteins (HSPs) to support elevated mitochondrial metabolism and counteract cell death factors. The investigational new drug SHetA2 targets these vulnerabilities in ovarian and endometrial cancer cells by disrupti...
Autores principales: | Rai, Rajani, Chandra, Vishal, Kennedy, Amy L., Zuna, Rosemary E., Benbrook, Doris Mangiaracina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531157/ https://www.ncbi.nlm.nih.gov/pubmed/36203464 http://dx.doi.org/10.3389/fonc.2022.958536 |
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