Distinct functions of dimeric and monomeric scaffold protein Alix in regulating F-actin assembly and loading of exosomal cargo

Alix is a ubiquitously expressed scaffold protein that participates in numerous cellular processes related to the remodeling/repair of membranes and the actin cytoskeleton. Alix exists in monomeric and dimeric/multimeric configurations, but how dimer formation occurs and what role the dimer has in A...

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Detalles Bibliográficos
Autores principales: Qiu, Xiaohui, Campos, Yvan, van de Vlekkert, Diantha, Gomero, Elida, Tanwar, Ajay C., Kalathur, Ravi, Weesner, Jason A., Bongiovanni, Antonella, Demmers, Jeroen, d’Azzo, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531180/
https://www.ncbi.nlm.nih.gov/pubmed/36030822
http://dx.doi.org/10.1016/j.jbc.2022.102425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531180/
https://www.ncbi.nlm.nih.gov/pubmed/36030822
http://dx.doi.org/10.1016/j.jbc.2022.102425

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