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Distinct functions of dimeric and monomeric scaffold protein Alix in regulating F-actin assembly and loading of exosomal cargo
Alix is a ubiquitously expressed scaffold protein that participates in numerous cellular processes related to the remodeling/repair of membranes and the actin cytoskeleton. Alix exists in monomeric and dimeric/multimeric configurations, but how dimer formation occurs and what role the dimer has in A...
Autores principales: | Qiu, Xiaohui, Campos, Yvan, van de Vlekkert, Diantha, Gomero, Elida, Tanwar, Ajay C., Kalathur, Ravi, Weesner, Jason A., Bongiovanni, Antonella, Demmers, Jeroen, d’Azzo, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531180/ https://www.ncbi.nlm.nih.gov/pubmed/36030822 http://dx.doi.org/10.1016/j.jbc.2022.102425 |
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