Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin

Spinal cord injury (SCI) is the most severe result of spine injury, but no effective therapy exists to treat SCI. We have previously shown that the E3 ubiquitin ligase Two RING fingers and DRIL 1 (Triad1) promotes neurite outgrowth after SCI. However, the mechanism by which Triad1 affects neuron gro...

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Detalles Bibliográficos
Autores principales: Wu, Chunshuai, Xu, Guanhua, Bao, Guofeng, Gao, Hong, Chen, Jiajia, Zhang, Jinlong, Chen, Chu, Hong, Hongxiang, Xue, Pengfei, Jiang, Jiawei, Liu, Yang, Huang, Jiayi, Sun, Yue, Fu, Jiawei, Li, Yiqiu, Cui, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531182/
https://www.ncbi.nlm.nih.gov/pubmed/36055408
http://dx.doi.org/10.1016/j.jbc.2022.102443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531182/
https://www.ncbi.nlm.nih.gov/pubmed/36055408
http://dx.doi.org/10.1016/j.jbc.2022.102443

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