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Rethinking detection of pre-existing and intervening Plasmodium infections in malaria clinical trials

Pre-existing and intervening low-density Plasmodium infections complicate the conduct of malaria clinical trials. These infections confound infection detection endpoints, and their immunological effects may detract from intended vaccine-induced immune responses. Historically, these infections were o...

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Detalles Bibliográficos
Autores principales: Owalla, Tonny J., Hergott, Dianna E. B., Seilie, Annette M., Staubus, Weston, Chavtur, Chris, Chang, Ming, Kublin, James G., Egwang, Thomas G., Murphy, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531235/
https://www.ncbi.nlm.nih.gov/pubmed/36203582
http://dx.doi.org/10.3389/fimmu.2022.1003452