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Identification and Characterization of a Cryptic Bifunctional Type I Diterpene Synthase Involved in Talaronoid Biosynthesis from a Marine-Derived Fungus

[Image: see text] We report the identification of the tnd biosynthetic cluster from the marine-derived fungus Aspergillus flavipes and the in vivo characterization of a cryptic type I diterpene synthase. The heterologous expression of the bifunctional terpene synthase led to the discovery of a diter...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Wu, Guangwei, Heard, Stephanie C., Niu, Changshan, Bell, Stephen A., Li, Fengli, Ye, Ying, Zhang, Yonghui, Winter, Jaclyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531244/
https://www.ncbi.nlm.nih.gov/pubmed/36126322
http://dx.doi.org/10.1021/acs.orglett.2c02904