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Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease

A main pathological event in Alzheimer’s disease is the generation of neurofibrillary tangles originating from hyperphosphorylated and subsequently aggregated tau proteins. Previous reports demonstrated the critical involvement of members of the protein kinase family CK1 in the pathogenesis of Alzhe...

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Detalles Bibliográficos
Autores principales: Roth, Aileen, Sander, Annabelle, Oswald, Marleen Silke, Gärtner, Fabian, Knippschild, Uwe, Bischof, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531328/
https://www.ncbi.nlm.nih.gov/pubmed/36203870
http://dx.doi.org/10.3389/fmolb.2022.872171