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Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues

BACKGROUND: Optimal cytoreduction to no residual disease (R0) correlates with improved disease outcome for high-grade serous ovarian cancer (HGSOC) patients. Treatment of HGSOC patients with neoadjuvant chemotherapy, however, may select for tumor cells harboring alterations in hallmark cancer pathwa...

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Detalles Bibliográficos
Autores principales: Penick, Emily R., Bateman, Nicholas W., Rojas, Christine, Magana, Cuauhtemoc, Conrads, Kelly, Zhou, Ming, Hood, Brian L., Wang, Guisong, Parikh, Niyati, Huang, Ying, Darcy, Kathleen M., Casablanca, Yovanni, Mhawech-Fauceglia, Paulette, Conrads, Thomas P., Maxwell, G. Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531351/
https://www.ncbi.nlm.nih.gov/pubmed/36195845
http://dx.doi.org/10.1186/s12014-022-09372-y