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Structural modeling of protein ensembles between E3 RING ligases and SARS-CoV-2: The role of zinc binding domains

BACKGROUND: The ubiquitin system is a modification process with many different cellular functions including immune signaling and antiviral functions. E3 ubiquitin ligases are enzymes that recruit an E2 ubiquitin-conjugating enzyme bound to ubiquitin in order to catalyze the transfer of ubiquitin fro...

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Detalles Bibliográficos
Autores principales: Chasapis, Christos T., Perlepes, Spyros P., Bjørklund, Geir, Peana, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531365/
https://www.ncbi.nlm.nih.gov/pubmed/36209710
http://dx.doi.org/10.1016/j.jtemb.2022.127089