Metabolic control analysis enables rational improvement of E. coli l-tryptophan producers but methylglyoxal formation limits glycerol-based production

BACKGROUND: Although efficient l-tryptophan production using engineered Escherichia coli is established from glucose, the use of alternative carbon sources is still very limited. Through the application of glycerol as an alternate, a more sustainable substrate (by-product of biodiesel preparation),...

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Detalles Bibliográficos
Autores principales: Schoppel, Kristin, Trachtmann, Natalia, Korzin, Emil J., Tzanavari, Angelina, Sprenger, Georg A., Weuster-Botz, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531422/
https://www.ncbi.nlm.nih.gov/pubmed/36195869
http://dx.doi.org/10.1186/s12934-022-01930-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531422/
https://www.ncbi.nlm.nih.gov/pubmed/36195869
http://dx.doi.org/10.1186/s12934-022-01930-1

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