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Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice

BACKGROUND: Moderate physical exercise is conducive to the brains of healthy humans and AD patients. Previous reports have suggested that treadmill exercise plays an anti-AD role and improves cognitive ability by promoting amyloid clearance, inhibiting neuronal apoptosis, reducing oxidative stress l...

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Detalles Bibliográficos
Autores principales: Xu, Longfei, Li, Mingzhe, Wei, Aili, Yang, Miaomiao, Li, Chao, Liu, Ran, Zheng, Yuejun, Chen, Yuxin, Wang, Zixi, Wang, Kun, Wang, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531430/
https://www.ncbi.nlm.nih.gov/pubmed/36195875
http://dx.doi.org/10.1186/s12974-022-02607-7