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Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice
BACKGROUND: Moderate physical exercise is conducive to the brains of healthy humans and AD patients. Previous reports have suggested that treadmill exercise plays an anti-AD role and improves cognitive ability by promoting amyloid clearance, inhibiting neuronal apoptosis, reducing oxidative stress l...
Autores principales: | Xu, Longfei, Li, Mingzhe, Wei, Aili, Yang, Miaomiao, Li, Chao, Liu, Ran, Zheng, Yuejun, Chen, Yuxin, Wang, Zixi, Wang, Kun, Wang, Tianhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531430/ https://www.ncbi.nlm.nih.gov/pubmed/36195875 http://dx.doi.org/10.1186/s12974-022-02607-7 |
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