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Preclinical development of carrier-free prodrug nanoparticles for enhanced antitumor therapeutic potential with less toxicity
BACKGROUND: Nanomedicine has emerged as a promising strategy for cancer treatment. The most representative nanomedicine used in clinic is PEGylated liposomal doxorubicin DOXIL(®), which is first FDA-approved nanomedicine. However, several shortcomings, such as low drug loading capacity, low tumor ta...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531438/ https://www.ncbi.nlm.nih.gov/pubmed/36195911 http://dx.doi.org/10.1186/s12951-022-01644-x |